Pathogenic role of anti-ß2-glycoprotein I antibodies in antiphospholipid associated fetal loss: characterisation of ß2-glycoprotein I binding to trophoblast cells and functional effects of anti-ß2-glycoprotein I antibodies in vitro

摘要

Background: Antiphospholipid antibodies reacting with ß2-glycoprotein I (ß2GPI) have been associated with recurrent fetal loss and pregnancy complications.